About Ranexa treatment

Be proactive. Become an active participant in your treatment story. Learn how Ranexa may help manage your chronic angina symptoms.

Ranexa is used to treat adults with angina that keeps coming back, also known as chronic angina. Ranexa may be used with other medicines that are used for heart problems and blood pressure control. Discover how Ranexa may help you reach your goal of angina control.

Gain perspective on Ranexa and its impact on angina symptoms

The CARISA study was a 12-week clinical trial of about 800 patients with chronic angina. About a third of the patients took Ranexa (ranolazine) 1000 mg and their regular angina medicines. Another group of patients took their regular medicines without Ranexa. The average age of patients in the study was 64 years old. Over 75% of them were men.1,2

The study showed that, compared to patients taking their regular angina medicines without Ranexa, patients taking Ranexa had2:


More time walking

Exercise time on a treadmill stress test went up by 24 seconds.


Fewer angina attacks

Patients taking Ranexa had fewer angina attacks per week. The number of angina attacks per week was lowered by more than 30% (3 versus 2).


Less nitroglycerin use

Patients taking Ranexa used fewer nitroglycerin tablets per week. The number of tablets taken per week was lowered by more than 30% (3 versus 2).

Not all patients respond to Ranexa the same way. Men improved more than women in exercise time and in lowering the number of angina attacks per week. In the CARISA study, the most common side effects reported were constipation, dizziness, nausea, and weakness.1,2

“I’m starting to feel very comfortable with my treatment plan. Very comfortable with that, I’m just focused on life.”

-Robert, chronic angina patient


  1. Ranexa US full Prescribing Information. Gilead Sciences, Inc. Foster City, CA. January 2016.
  2. Chaitman BR, Pepine CJ, Parker JO, et al. Effects of ranolazine with atenolol, amlodipine, or diltiazem on exercise tolerance and angina frequency in patients with severe chronic angina: a randomized controlled trial. JAMA. 2004;291:309-316.

What important information should I know about Ranexa?

Get a better understanding of what Ranexa is and learn about possible side effects that may occur with treatment.

Remember, it's always important to keep your doctor updated if you have any side effect that bothers you or does not go away.

Looking for treatment savings?

For commercially insured patients who qualify, Ranexa Connect offers valuable savings options to use toward your treatment.

See if you may be eligible to save today with Ranexa Connect. Terms and conditions apply. For more details, go here.

Information Safety Information

Who should not take Ranexa?

Do not take Ranexa if: